READING GUIDE · Questions worth asking

GLP-1 Consultation Questions, Organized by Topic

Prepare for a conversation about health history, medicines, expected benefits, risks and costs—with specific questions prompted by six programs’ public documentation.

A useful GLP-1 consultation should leave you with more than a yes-or-no answer about a prescription. You should understand what treatment is being considered, why it might fit your circumstances, what remains uncertain and who will help after the first order. NIDDK organizes medication decisions around benefits, side effects, health conditions, other medicines, family history and costs. Those topics make a better appointment agenda than starting with an advertised monthly price or a promised weight-loss percentage.

This guide turns those topics into practical questions for U.S. adults, using examples from CoreAge Rx, Ro, Enhance.MD, Sesame, Walgreens and Found. Their consulted pages show why preparation matters: consultation formats differ, medication and membership charges may be separate, and some policies conflict. Public documentation was consulted October 19, 2026; that does not mean every page was updated then. Bring your questions to the treating clinician and direct account-specific billing questions to the program rather than treating this guide as individualized advice.

At a glance

What belongs in the discussion
NIDDK identifies benefits, side effects, current health conditions, other medicines, family history and costs as medication-selection considerations.
Sources: [2]
Membership is not necessarily medicine
Ro Body and Success by Sesame exclude medication costs from their subscription fees.
Sources: [6] [30]
Consultation format can depend on payment
Found describes synchronous video visits before each refill with insurance, versus mostly asynchronous text-based care for cash-pay patients.
Sources: [31]
Follow-up chat can carry a charge
Walgreens advertises initial visits starting at $49 and follow-up chat or additional video visits at $49 each, excluding medication.
Sources: [20]
Compounded products need a separate discussion
FDA recommends compounded drugs when an individual’s medical needs cannot be met by an approved drug; compounded preparations are not FDA approved.
Sources: [1]

Health history: What information will change the decision?

Start with: “What do you need to know about my health history, family history, allergies and pregnancy plans before discussing options?” NIDDK advises discussing these subjects with the clinician. Ask which records to gather and whether earlier treatment experiences matter. General adult BMI thresholds discussed by NIDDK are 30 or higher, or 27 or higher with weight-related health problems, but a threshold alone does not establish eligibility. The consultation should explain the applicable medication and program criteria, not simply confirm a questionnaire score.

Programs request different preparation. CoreAge Rx’s policy allows requests for health history, current medicines, identification, photographs, laboratory results, medical records and primary-care documentation, depending on treatment. Ro begins with medical history, lifestyle and goals and may request a metabolic laboratory test. Enhance.MD requires identity verification, including a full-face photograph and government-issued ID. Ask which items are required before payment, which can follow later and whether missing documentation delays clinical review.

Sources: [2] [7] [19] [13]

Current medicines: What exactly are we considering?

Bring a list of prescription medicines, nonprescription medicines, supplements and allergies. Ask: “How does each item affect the options you are considering, and what exact product, ingredients, route and presentation would you prescribe?” NIDDK recommends discussing medicines and supplements rather than making changes independently. Our guide to identifying the medicine behind an offer provides a companion checklist. A brand name, an active ingredient and a program’s marketing label are not interchangeable descriptions of what a pharmacy will dispense.

For example, CoreAge Rx says its compounded tirzepatide typically contains B-12; an alternative without B-12 requires discussion with the provider. Enhance.MD markets Core as semaglutide, Advanced as compounded tirzepatide and Elite as an injectable combination of semaglutide and tirzepatide. Ro identifies its Wegovy pill as oral semaglutide and Wegovy pen as an injection presentation. Ask the clinician to identify the actual proposed prescription and explain the rationale without assuming these offerings have interchangeable evidence.

Benefits: What would count as a useful response?

Ask: “What benefits are we aiming for, how will we assess response, and when will we reconsider the plan?” NIDDK describes medicines as accompanying healthy eating and physical activity, not replacing them. It also explains that duration depends on response and side effects and that obesity may require long-term care. Request a discussion of meaningful goals and reassessment rather than a promised result or an assumption that benefits will remain unchanged after treatment stops.

If an advertisement cites research, ask whether it studied the exact product and route being proposed. STEP 1 and SURMOUNT-1 did not measure outcomes for these telehealth programs, their compounded formulations, vitamin blends or microdosing offerings. CoreAge Rx markets semaglutide and tirzepatide “Microdosing Therapy,” while Found also advertises compounded semaglutide microdosing. Those offerings are documented commercial options, not proof that standard trial findings apply to them. Ask what evidence supports the specific proposal and what remains unestablished.

Sources: [2] [3] [4] [17] [18] [11]

Risks: What instructions and escalation plan will I receive?

Ask the clinician to explain common side effects, potentially serious concerns, monitoring and whom to contact if problems develop. Request product-specific written instructions and an explanation of anything unclear before administration. FDA has received reports of errors measuring or administering compounded GLP-1 medication, including errors associated with hospitalization. This makes instruction quality a practical consultation topic, not a reason to calculate a dose from an online article. Ask who can clarify the pharmacy label and demonstrate the supplied equipment.

For a compounded proposal, ask why an FDA-approved drug would not meet your medical needs. FDA recommends compounded drugs for that circumstance, with a prescription and a state-licensed pharmacy. Compounded preparations do not undergo FDA premarket review for safety, effectiveness and quality; that does not by itself prove clinical inequivalence. Approval concerns a particular product, not a clinic. Separately, ask for a delivery-problem plan: FDA explicitly advises not using an injectable GLP-1 that arrives warm or insufficiently refrigerated and contacting the provider or pharmacy.

Sources: [1] [2]

Care responsibilities: Who evaluates, prescribes and follows up?

Ask for the treating practice’s name, the clinician’s professional role, the consultation format and the follow-up schedule. CoreAge Rx’s legal footer separates its administrative platform from independent professional entities responsible for evaluation and prescribing. Enhance.MD likewise distinguishes its platform from medical groups and says payment does not guarantee prescribing or dispensing. Sesame describes affiliated practices as independently owned and operated. These are provider statements, not independent credential checks. Request the names relevant to your care rather than assuming the website brand is the medical practice.

Next ask: “Who answers a medical message, how quickly should I expect a response, and what costs extra?” Ro advertises unlimited provider messaging, check-ins and coaching. Walgreens uses video for its general initial pathway and mostly chat for follow-up, with visit charges. CoreAge Rx advertises ongoing provider access, but a “24/7 Provider Support” heading is explained with customer-support availability. Our follow-up support questions help distinguish clinician access, pharmacy assistance, administrative help and automated tools.

Costs: What will the first payment and later payments cover?

Ask for a written breakdown separating consultation, membership, medicine, supplies, laboratory work and shipping. Ro advertises membership at $39 for the first month, then $149 monthly on its monthly plan; its advertised rate as low as $74 per month requires annual prepayment. Medication is additional. Sesame advertises subscriptions starting at $59 per month with an annual subscription and $99 for its month-to-month option, with medication separate and some clinicians charging more. These figures describe different purchases, not comparable all-in treatment quotes.

Billing periods deserve their own question. Sesame calls its option monthly but elsewhere specifies advance billing every 28 days. Enhance.MD’s Core injection page lists $249 per month for its one-month option, billed every four weeks, with $50 off the first order; longer-plan prices have different billing intervals and discounts. Ask for the actual collection date, amount and renewal calendar. Use our price-question checklist to record answers instead of assuming four weeks equals a calendar month.

Five cost questions to put in writing
TopicQuestionDocumented reason to ask
MembershipIs medication separate?Ro and Sesame exclude medication from subscription fees.
Visit chargesDoes a follow-up message become a paid visit?Walgreens lists follow-up chat visits at $49 each.
LaboratoriesWhich facility and state qualify for included testing?Sesame’s included Quest testing has state exclusions.
Payment intervalIs this a calendar month or 28 days?Sesame’s billing descriptions differ.
Longer plansWhat is collected now, and what is refundable?Enhance.MD lists multiple billing intervals; unused-prepayment rules remain unclear.
Sources: [6] [30] [8]

Insurance and pharmacy: Which route actually applies to me?

Ask the program and your health plan separate questions: “Do you accept insurance for visits?” and “Does my plan cover this exact medication and presentation?” Ro’s insurance concierge currently covers only Wegovy pen, Zepbound autoinjector pen and Ozempic; insurance does not cover its membership. Walgreens does not accept insurance for Weight Management visits but advertises prior-authorization support for eligible commercially insured patients. Found’s insurance-priced compounded plans reflect coverage for clinical care, not insurance payment for the compounded medicine, and visit copays may apply. Also ask: “Does my insurance enrollment affect whether I can use this program?” Ro says patients with Medicaid and some other government-funded plans are currently ineligible for treatment. Found’s general insurance-price terms exclude government plans, while a separate page advertises a Medicare pathway; confirm which terms apply. Sesame’s telemedicine terms require patients to certify that they are not federal health-program beneficiaries.

Ask which pharmacy will receive the prescription and whether a quoted price requires that channel. CoreAge Rx’s FAQ requires its affiliated network, while its terms allow requesting a pharmacy of choice before completing an order; get that conflict resolved. Enhance.MD allows an outside pharmacy but says medication is then billed directly. Ro says cash-pay prescriptions sent to its pharmacies or partners ship within a week once prescribed; that is dispatch, not guaranteed arrival. Request separate estimates for review, authorization, preparation, shipment and delivery.

Before leaving: What happens if the plan changes?

Ask what happens financially if you are ineligible, prefer not to proceed or cannot obtain the medication. CoreAge Rx’s FAQ promises a full refund if no prescription is approved, but its policy retains an applicable $50–$100 consultation fee. That policy also makes prescription sales final after approval and transmission to the pharmacy—even before shipment—and generally makes orders nonrefundable after 30 calendar days, subject to applicable law. These boundaries make the timing of documentation and clinical review important questions before purchasing.

Separate stopping future charges from recovering past payments. Sesame’s program page allows self-cancellation before the next cycle, while general terms require email or phone cancellation at least 48 hours before renewal processing. Found recommends cancellation or pausing at least 48 hours before renewal and says renewal payments are nonrefundable. Request written confirmation of the rule applying to your plan, particularly a prepaid option. Our renewal questions can help turn the answer into a dated reminder rather than an assumption.

Sources: [14] [7] [30] [10] [22]

Questions & answers

What should I clarify with CoreAge Rx before paying?

Ask when the card is charged, whether the order is one-time or an optional subscription, and what refund applies if prescribing is declined. Its FAQ describes both charging before review and billing at shipment. The help center describes optional subscriptions, while the FAQ denies auto-rebilling. Obtain an order-specific explanation rather than choosing whichever statement sounds most favorable.

Sources: [14] [32] [7]
What should I ask Ro if insurance approval takes time?

Ask when membership billing begins, what services you can use during the wait and what cancellation means if coverage is denied. Ro estimates one to three weeks for insurance coordination and about one to two weeks for prior-authorization review. It offers cash-pay alternatives or membership cancellation if coverage is unavailable, but the consulted documentation does not resolve general prepaid-plan refund rules.

Sources: [27] [6]
What should I ask Enhance.MD about laboratory work?

Confirm whether testing precedes your consultation and which tests apply to your selected program. Its process page describes baseline CMP, TSH, lipids and A1c testing at Quest Diagnostics. The FAQ describes results arriving in approximately one to two business days after testing, followed by an invitation to schedule video care. That interval is not a medication-delivery estimate.

Sources: [5] [13]
What should I ask Sesame about extra testing charges?

Ask whether your chosen testing location qualifies for included laboratory work. Sesame limits included testing to Quest facilities and excludes those in Arizona, Hawaii, North Dakota, New Jersey, New York, Oklahoma, Rhode Island, South Dakota and Wyoming. In those states, laboratory fees are additional to the subscription. Confirm the facility before treating testing as included in your budget.

Sources: [30]
Does Walgreens’ pharmacy chat replace a follow-up appointment?

Do not assume so. Walgreens advertises pharmacy-expert chat around the clock, with possible waits, and says it is not for emergencies or a substitute for physician advice. Weight Management follow-up chat visits are separately advertised at $49 each. Ask which channel handles your question, whether it creates a paid visit and when the prescriber will respond.

Sources: [28] [20]
What should I ask Found if I want one particular medication?

Ask what happens if that medicine is declined but another treatment remains available. Found says ineligibility for a preferred medication alone does not qualify for a membership refund when other options remain suitable under its program. Also ask about appointment obligations: its billing consent specifies a $30 charge for a missed scheduled consultation or cancellation with less than 24 hours’ notice.

Sources: [22] [33]

Our assessment

A prepared consultation can clarify both medical choices and the service you are buying. These programs document useful features, including video visits, messaging, laboratory arrangements and pharmacy coordination, but the details differ substantially. Bring your health and medication information, ask what supports the exact proposed treatment, and obtain written answers about follow-up, payment and cancellation. Where public pages conflict, provider confirmation is necessary; a low advertised price or convenient intake process cannot resolve the medical decision.

Sources & documentation

Public materials consulted October 19, 2026. Provider statements are attributed claims, not independently verified clinical outcomes. Terms can change; obtain a current written quote.

  1. FDA concerns with unapproved GLP-1 drugs used for weight loss ↗
  2. NIDDK: prescription medications for overweight and obesity ↗
  3. Wilding et al. (2021): STEP 1 semaglutide trial ↗
  4. Jastreboff et al. (2022): SURMOUNT-1 tirzepatide trial ↗
  5. Enhance.MD — how it works ↗
  6. Ro — weight loss/pricing ↗
  7. CoreAge Rx — returns refund policy ↗
  8. Enhance.MD — product/core semaglutide ↗
  9. Sesame / Success by Sesame — official website ↗
  10. Sesame / Success by Sesame — terms of service ↗
  11. Found — microdosing ↗
  12. Enhance.MD — official website ↗
  13. Enhance.MD — faq ↗
  14. CoreAge Rx — faq ↗
  15. Found — medicare weight loss ↗
  16. Ro — weight loss/wegovy pill ↗
  17. CoreAge Rx — product/semaglutide microdosing therapy ↗
  18. CoreAge Rx — product/tirzepatide microdosing therapy ↗
  19. Ro — weight loss/how it works ↗
  20. Walgreens / Walgreens Weight Management — topic/virtual healthcare/weight loss.jsp ↗
  21. CoreAge Rx — official website ↗
  22. Sesame / Success by Sesame — terms/offer terms v3 ↗
  23. CoreAge Rx — terms ↗
  24. Enhance.MD — product/advanced tirzepatide ↗
  25. Ro — weight loss/wegovy ↗
  26. CoreAge Rx — product/semaglutide ↗
  27. Ro — weight loss/insurance ↗
  28. Walgreens / Walgreens Weight Management — topic/pharmacy.jsp ↗
  29. Ro — weight loss ↗
  30. Sesame / Success by Sesame — service/online weight loss program ↗
  31. Sesame / Success by Sesame — insurance ↗
  32. CoreAge Rx — es/primeros pasos/acerca de coreage rx ↗
  33. Sesame / Success by Sesame — terms/payment and billing consent ↗
  34. Enhance.MD — product/elite tirzepatide and semaglutide ↗

Continue reading